Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components ...

The researchers found that Zeb2 acts as a master switch. When the gene is active, it turns macrophages into cancer supporters ...

Building on grounding-breaking research into the immuno-suppressive role of tumor-associated macrophages (TAMs), Macomics has developed a unique platform, ENIGMAC combining a human bioinformatic ...

Through CRISPR-Cas9 gene editing and single-cell analysis, they zeroed in on a gene named Zeb2.

The researchers found that Zeb2 acts as a master switch. When the gene is active, it turns macrophages into cancer supporters. When silenced, macrophages revert to their natural, cancer-fighting role.

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an estimated €20,000 per patient, per year with an overall cost to the health ...