This regimen change is based on evidence of the efficacy equivalence of these two drugs and the lack of an increase in overall toxic effects when capecitabine is used. Many investigators in ...

During the first cycle of capecitabine development, three concomitant drugs were found to affect 5-FU clearance. [5] Paracetamol and morphine increased 5-FU clearance by 26% and 41%, respectively ...

DPD is the abbreviation for the enzyme that metabolizes 5-FU and Xeloda. How both of those drugs are broken down by the body is regulated by that enzyme, and deficiency of that enzyme means that the ...