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Bispecific Antibodies in Hematologic and Solid Tumors: Current Landscape and Therapeutic Advances
Over the past two decades, monoclonal antibodies (mAbs) have played a pivotal role in cancer treatment; however, their efficacy as anticancer agents is constrained by tumor heterogeneity and the ...
ascopubs.org13d
Treatment Innovations in Pancreatic Cancer: Putting Patient Priorities First
Emerging Paradigms in Genitourinary Cancers: Integrating Molecular Imaging, Hypoxia-Inducible Factor–Targeted Therapies, and Antibody-Drug Conjugates in Renal Cell and Urothelial Carcinomas Pancreatic ...
ascopubs.org4d
Endocrine Therapy Omission in Estrogen Receptor–Low (1%-10%) Early-Stage Breast Cancer
Overall Survival Analysis of the Phase III CodeBreaK 300 Study of Sotorasib Plus Panitumumab Versus Investigator's Choice in Chemorefractory KRAS G12C Colorectal Cancer Using the National Cancer ...
ascopubs.org4d
Novel Postneoadjuvant Prognostic Breast Cancer Staging System
Overall Survival Analysis of the Phase III CodeBreaK 300 Study of Sotorasib Plus Panitumumab Versus Investigator's Choice in Chemorefractory KRAS G12C Colorectal Cancer Prognostic staging after ...
ascopubs.org12d
Constitutional Epimutations: From Rare Events Toward Major Cancer Risk Factors?
Cancers are predominantly characterized by their genomic aberrations, but over the past decades, there has also been an increasing focus on epigenetic alterations in cancer biology. 12-15 Although ...
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Systemic Therapies for Advanced Hepatocellular Carcinoma: Which Gaps Should We Try to Fill?
Educational Video as an Alternative to Pretest In-Person Genetic Counseling in Candidates for Cancer Genetic Testing: A Randomized Controlled Noninferiority Trial Hepatocellular carcinoma (HCC) is the ...
ascopubs.org11d
Phase I Study of Subcutaneous Rituximab Hyaluronidase Combined With CHOP Chemotherapy for the Treatment of Diffuse Large B-Cell Lymphoma in Uganda
Pacific Peoples' Experiences of Cancer and Its Treatment in Aotearoa New Zealand Through Talanoa: A Qualitative Study of Samoan and Tongan Participants This open-label phase I study enrolled patients ...
ascopubs.org5d
They Not Like Us: Evaluating the Diverse Strategies in Locally Advanced Rectal Cancer Treatment
The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...
ascopubs.org4d
Drug Shortages Demand Action: Policy Changes to Protect Patient Care
Both the magnitude and persistence of drug shortages highlight the need to elucidate the underlying factors that disrupt the production and distribution of essential pharmaceuticals. At the federal ...
ascopubs.org4d
Development of a Machine Learning Algorithm to Predict Abnormalities in Serum Phosphate in a Large Oncology Cohort
Risk Stratification for Sentinel Lymph Node Positivity in Older Women With Early-Stage Estrogen Receptor–Positive/Human Epidermal Growth Factor Receptor 2 Neu–Negative Invasive Breast Cancer This ...
ascopubs.org8d
High-Dose Methotrexate in Children and Young Adults With ALL and Lymphoblastic Lymphoma: Results of the Randomized Phase III Study UKALL 2011
Neoadjuvant FOLF(IRIN)OX Chemotherapy for Resectable Pancreatic Adenocarcinoma: A Multicenter Randomized Noncomparative Phase II Trial (PANACHE01 FRENCH08 PRODIGE48 study) R1 compared induction ...
ascopubs.org4d
Incorporating Targeted Therapy Into Neuro-Oncology Practice
The integration of targeted therapies into neuro-oncology is revolutionizing the management of primary CNS malignancies. Advances in sequencing technologies and the incorporation of molecular ...