† VIMs are made up of 266 amino acid residues with the exception of VIM-7 (265 residues) and VIM-18 (262 residues). VIM-21, -22 and -27 have been assigned in the Lahey Clinic [201], but there ...

Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California 94025, United States ...

This project will develop state of the art wearable sensors to measure antimicrobial resistance, which is key to prevent antibiotic misuse.

Structural Comparison of SHV-1 (PDB ID: 3N4I) and PDC-3 (PDB ID: 4HEF) β-Lactamases. Catalytic serine S 70 (SHV-1) and S 64 (PDC3) are highlighted using stick representation. Important loops ...

北京大学化学与分子工程学院季者课题组诚聘博士后和科研助理，开展生物物理方面的工作。以生物大分子、细胞和组织为研究对象，利用振动和荧光光谱及成像技术，探测生命系统的化学多样性，发展生物分子识别检测方法。实验室能够提供便利的实验条件、有竞争力的课题、团结互助的组内氛围、以及临床合作机会。

本研究构建了针对铜绿假单胞菌（Pseudomonas aeruginosa）的抗生素评估系统，为开发新型抗生素提供了有力工具。 在当今全球细菌感染问题日益严峻的背景下，抗生素耐药性已成为一个慢性大流行病问题。2016年，被忽视疾病药物研发倡议（Drugs for Neglected Diseases ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

This important study describes how a single effector of the Type Six Secretion System (T6SS) has two distinct functions, which may contribute to bacterial survival and the development of novel ...