Researchers from the University of Barcelona and collaborators reported the discovery and preclinical characterization of novel imidazoline I2 receptor ligands (I2-IRs). Among the series, the most ...

Tizanidine, a muscle relaxant, exerts its mechanism as a centrally acting alpha-2 adrenergic receptor agonist and binds to imidazoline receptors. Bradycardia and hypotension are adverse effects ...

The Last of Us Part 2 Remastered will release on April 3, 2025, for players on PC. As revealed during The Game Awards 2024, the Ellie-focused sequel heads to PC with a few upgrades beyond the ...

The proposed coating releases corrosion inhibitors from the microcapsules upon damage, enabling autonomous repair. Microcapsules were fabricated with an oil-soluble imidazoline oleate corrosion ...

Over the years, scientists have studied several compounds that might slow aging, such as metformin (a diabetes drug), ...

Death Stranding 2 is coming our way, with the official reveal of a June release date confirming we won't have to wait much longer to step into the adventure for ourselves. Officially called Death ...

Scientists have identified a widely prescribed hypertension drug as a potential key to extending lifespan and slowing aging.

TL;DR: AMD is bringing in a next-gen AFMF, version 2.1, that's expected to launch with its RX 9070 GPUs, benefiting from enhanced image quality while still working with existing GPUs - it won't be ...

During the eight-week treatment phase, patients received either moxonidine (0.2 or 0.4 mg/day) or the ACE inhibitor ramipril (2.5 or 5 mg/day). Conclusions: Moxonidine and ramipril exhibited ...