The dynamic spatial chromosomal configurations in 3D space demonstrate cell-to ... identify a distinct chromatin structure at clustered GBP innate immune genes that preserves a mitotically ...

Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a ...

Epigenetic regulation, including the three-dimensional (3D) architecture of the genome, plays a critical role in gene expression and cellular function. Aberrations in chromatin organization are ...

The study found that UV radiation significantly alters the 3D genome structure, leading to distinct changes in chromatin interactions and gene regulation. Specifically, the researchers observed ...

Understanding chromosome organisation in three-dimensional (3D) space is essential for identifying long-range contacts between ... Methods Primary chondrocytes collected from 8 patients with knee ...

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Introduction:: Hi-C is a widely used technique for mapping chromosomal interactions within a 3D genomic framework, however ... studies were integrated to enhance the resolution of chromatin ...

A team of Penn State researchers has used a new 3D-printing method to produce a complex metal build that was once only possible with welding: fusing two metals together into a single structure. Using ...

April 3, 2025) Chromatin remodeling plays a vital role in gene regulation ... The researchers gauged the functional importance of various interactions within the structure by introducing specific ...

Locusts, as devastating pests, can reversibly transform between solitary individuals and gregarious swarms with markedly different behaviors. Epigenetic regulation orchestrated by changes in chromatin ...