No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

The potential of monoclonal antibodies (mAbs) as therapies is indisputable. The current mAbs market is expected to be around ~USD 150 billion. In 2021, five out of the top 10 selling drugs were ...

This Perspective article examines the interplay between antibody diversification mechanisms and highlights the importance of constant regions in influencing the specificity and functionality of ...

Antibodies have become the Swiss Army tool for molecular biology and nanotechnology. Their outstanding ability to specifically recognise molecular antigens allows their use in many different ...

College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for ...

NASHVILLE, Tenn. (WSMV) - Vanderbilt University Medical Center will lead a massive project aimed at discovering therapeutic antibodies through the use of Artificial Intelligence. Therapeutic ...

These two cell types have different roles. B lymphocytes produce antibodies and help alert the T lymphocytes. T lymphocytes destroy compromised cells in the body and help to alert other leukocytes.

ARTEMIS is a US-based study evaluating a single administration of Ixo-vec (6E10 vg/eye) compared to aflibercept (2mg) every 8 weeks in approximately 284 patients with wet AMD, including both treatment ...

Each type of lymphocyte fights infection differently. But the goal of protecting the body from infection remains the same. The B cells make specific antibodies to fight germs. The T cells kill the ...

研究发现，XXO（卵巢携带 XX 基因型）小鼠的皮层 6E10 免疫反应区域（IRA）和斑块数量明显多于 XY-T（睾丸携带 XY-Sry Sry + 基因型）小鼠。在神经炎症方面，XXO 小鼠的皮层 GFAP 和 IBA1 的 IRA 显著高于 XY-T 小鼠，且性别染色体和性腺对皮层 IBA1 + 细胞数量也有影响。