ACC is a classical downstream kinase of AMPK, which inhibits its activity through phosphorylation, thereby reducing DNL (19). In fatty acid oxidation, cytosolic fatty acids first bind with CoA under ...

2I). Consistently, the inhibition of fatty acid synthesis with a chemical inhibitor of Acc, induced drastic cell death in naïve ESCs (Fig. 2J). Overall, these results indicate that the constant ...

在研究结论和讨论部分，研究人员指出，本研究揭示了内皮 FAO 在糖尿病视网膜病变中血管渗漏的重要作用，发现人参皂苷 Rd 通过激活 GPR30 - AMPK 通路，促进 FAO，改善线粒体氧化应激，修复血视网膜屏障，为 DR 的治疗提供了新的代谢调节策略。然而，目前仍存在一些问题需要进一步研究，例如 Rd 对视网膜细胞的全面影响、与其他信号通路的相互作用，以及其在临床应用中的生物利用度、毒性等问题 ...

Reigniting ACC basketball starts with an obvious Step 1: Make good coaching hires. Your move, Virginia. Miami and Florida State bought low with unproven coaches. Gone are the days of Roy Williams ...

Out of the big conference matchups, the ACC Basketball Tournament kicks things off this week in North Carolina. GET: FUBOTV 7-DAY FREE TRIAL Want to watch the 2025 ACC Basketball Tournament on TV ...

While the Atlantic Coast Conference itself expanded this year, the ACC tournament did not. The event size was held at 15 teams, meaning the bottom three finishers in the now 18-team league won’t ...

The 2025 ACC Tournament starts Tuesday at Spectrum Center in Charlotte, but Duke basketball won’t play until Thursday. The Blue Devils (28-3, 19-1 ACC) enter the postseason as the top-ranked ...

Duke basketball, who recently rose to No. 1 in USA TODAY Sports' Coaches Poll for the first time this season, looks to sweep the ACC championships with a conference tournament win. The men's ACC ...

Ahead of this week's conference championship, Joe Lunardi's latest Bracketology projects the ACC to receive only three bids for the men's NCAA tournament on Selection Sunday. That would be its ...

Boston, USA-based biotech Nimbus Therapeutics today revealed that, along with partner Eli Lilly (NYSE: LLY), it has achieved a significant pre-clinical milestone in their research collaboration ...

On the other hand, it's great when a bubble team has a path laid out which will make it easy for the selection committee to offer a yes or no verdict. This is what we have in the 2025 ACC Tournament ...