The 370 kDa ATM protein has been suspected of possessing ... Other proteins that are targets of ATM kinase activity or other domains of ATM may have important roles in these pathological conditions.

The ATM protein is a key signaling kinase that is activated by DNA damage and ionizing ... In normal cells ATM is held in an inactive dimer in which the ATM kinase domain is bound to the ... Lab ...

The resulting mutant HTT protein elicits many toxic downstream ... To overcome this drawback, the team compared the ATP binding domains of Vsp34 with that of ATM. That revealed a handful of ...