Lately, Acetyl L-Carnitine, a known supplement, has attracted increasing attention. This supplement is a byproduct of L-Carnitine, an amino acid naturally present in the human body. Acetyl L ...

Sirt1 demonstrates deacetylation effects on PGC-1α, HMGB1, FOXOs, and p53. It hinders the activation of NLRP3 inflammasome and NF-κB while also engaging with AMPK. It regulates inflammatory response, ...

Diabetic kidney disease (DKD) is a prevalent complication of diabetes mellitus (DM), and its incidence is increasing alongside the number of diabetes cases. Effective treatment and long-term ...

State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), ChemBioMed Interdisciplinary Research Center, ...

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States Alnylam ...

2Dr. Li Dak-Sum Research Centre, the University of Hong Kong, Hong Kong 3Department of Surgery, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 4Department of Surgery, ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

Several supplements, including L-carnitine, have been studied for their effects on erectile dysfunction (ED). A 2024 meta analysis published in the Journal of Sexual Health found that a combination of ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...