Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Kyoto 615-8510, Japan ...

We present a one-step, visible light-induced synthesis of bicyclo[1.1.1]pentane-ketone, a bioisostere for benzoyl groups that ...

Since the 1990s, medicinal chemistry research has demonstrated that replacing benzene rings with bicyclo[1.1.1]pentane derivatives enhances drug ...

High-resolution mass spectrometry and radical trapping experiments further supported the involvement of acyl radicals, validating a radical-based mechanism. “In summary, we developed a one-step ...

Department of Chemistry, University of California, Irvine, Irvine, California 92697, United States ...

Free radicals are highly reactive and unstable molecules that are made by the body naturally as a byproduct of normal metabolism. Free radicals can also be made by the body after exposure to toxins in ...

These radicals propagate the reaction by reacting with oxygen to form lipid peroxyl radicals ... PUFA, Polyunsaturated Fatty Acid; ACSL4, Acyl-CoA Synthetase Long-chain Family Member 4; PUFA-CoA, ...