Monocytes and macrophages belong to the innate immune system and aging has a profound impact on these cells, leading to functional changes and most importantly, to the secretion of pro-inflammatory ...

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but ...

Telomere Length and Aging Telomeres, protective caps at the ... A clinical trial involving 161 participants revealed that the intake of Macrophage Activating Factor resulted in remarkable telomere ...

In aging mice, senescent cells in the choroid plexus recruited circulating macrophages. These immune cells released a protease, cathepsin S, that chewed up claudin 1, part of the glue that seals ...

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

Its progression relies on various mechanisms, among which the tumor microenvironment and tumor-associated macrophages (TAMs) have garnered increasing attention. Macrophage infiltration in various ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.