Array Bridge is testing promising drug candidates that can effectively bind and even degrade target proteins, but not via their active sites.

A new study published in Molecular Medicine Reports finds that nanoparticles made from Cannabis sativa stems could have ...

Disruptions to developmental cell signaling pathways and transcriptional cascades have been implicated in tumor initiation, maintenance and progression. Resurgence of aberrant neurodevelopmental ...

Both Samuel and David, as youths, fulfill God's will; David and Goliath (1 Sam. 17:26,34-37,47); David gains the heart of all (18:16); Saul's jealousy of David (18:9-11). And David said to Saul, Let ...

In this study, EL4 T cell lymphoma cells were found to show decreased ERK phosphorylation and increased apoptosis upon ligation ... The Ni study also showed that CD44v6 was responsible for activation ...

In amongst a clutch of discontinued phase 3 programmes in Roche's fourth-quarter results update was the news that it has stopped a study of AKT inhibitor ipatasertib as a treatment for first-line ...

Conclusion Our study uncovers a novel functional crosstalk between aberrant lipogenesis and cholesterol biosynthesis pathways in hepatocarcinogenesis, whose concomitant inhibition might represent a ...