Both WT and KO T cells initially up-regulated activation markers like CD69 and activated the PI3K/Akt/mTOR pathway as evidenced by pS6 expression ... A recent paper examined a B cell-specific deletion ...

New research has revealed that Schistosoma haematobium (S. haematobium), a parasitic infection affecting millions globally, ...

In amongst a clutch of discontinued phase 3 programmes in Roche's fourth-quarter results update was the news that it has stopped a study of AKT inhibitor ipatasertib as a treatment for first-line ...

Early-onset CRC (EO-CRC) was associated with Flavonifractor plautii and increased bile acid, tryptophan, and choline ...

In Ghana, where traditional medicine complements modern healthcare, an increasing number of women are exploring alternative treatments, including cannabis, for breast cancer symptom management .

New research has revealed that Schistosoma haematobium (S. haematobium), a parasitic infection affecting millions globally, can trigger cancer-related ...

A systematic review published in Discover Oncology explores the anticancer efficacy of medicinal plant extracts in treating Oral Squamous Cell Carcinoma (O | Plants And Animals ...

However, the evidence supporting some of the conclusions remains incomplete, and further mechanistic studies are needed to clarify how miR-283 affects normal aging and influences exercise adaptations.

近日，广东药科大学基础医学院李雄教授团队在《Oncogene》杂志上发表研究论文，揭示了线粒体外膜蛋白TOMM20通过调控雄激素受体（AR）蛋白稳定性及其转录活性促进前列腺癌进展的新机制。研究发现，TOMM20在前列腺癌组织和细胞中显著高表达，且与AR的表达水平呈正相关。TOMM20缺失显著减少了AR与基因启动子区域的结合，抑制基因转录。进一步研究表明，TOMM20通过SKP2介导的泛素化途径调控 ...

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