GART was significantly upregulated in lung cancer cells, repressed expression of GART markedly inhibited the proliferation and migration of lung cancer cells in vitro and in vivo. More importantly, ...

Cell proliferation is increased in tumours. OPN3 interacts with VEGFR2, forming a physical complex in HUVECs, and regulates angiogenesis in vitro and in vivo via the VEGFR2-mediated AKT pathway ...

Both WT and KO T cells initially up-regulated activation markers like CD69 and activated the PI3K/Akt/mTOR pathway as evidenced by pS6 expression ... A recent paper examined a B cell-specific deletion ...

New research has revealed that Schistosoma haematobium (S. haematobium), a parasitic infection affecting millions globally, ...

In amongst a clutch of discontinued phase 3 programmes in Roche's fourth-quarter results update was the news that it has stopped a study of AKT inhibitor ipatasertib as a treatment for first-line ...

Early-onset CRC (EO-CRC) was associated with Flavonifractor plautii and increased bile acid, tryptophan, and choline ...

PI3K/Akt/mTOR, Wnt/β-catenin, NF-κB, Notch, and DDR pathways. These pathways are critical in regulating essential cellular processes such as proliferation, survival, differentiation, and metastasis.

胆管癌（CCA）预后差，缺乏有效治疗手段。研究人员开展了异鼠李素（Iso）对 CCA 作用的研究。结果发现 Iso 可通过 PI3K/AKT 通路抑制 CCA 细胞增殖、侵袭和转移，AKT1 可能是其治疗 CCA 的靶点，为 CCA 治疗提供新方向。

In Ghana, where traditional medicine complements modern healthcare, an increasing number of women are exploring alternative treatments, including cannabis, for breast cancer symptom management .

The International Day for Disarmament and Non-Proliferation Awareness seeks to promote better awareness and understanding of disarmament issues among the public, especially young people.