Renal hypoperfusion occurs as a result of reduced cardiac output, resulting in the activation of the renin–angiotensin–aldosterone system, which compensates for the hypoperfusion. However ...

Munich news, health insurance, technology, jobs and other topics for expatriates. The Eye Newspapers covers daily news and offers services for foreigners.

Diabetic kidney disease (DKD), a common cause of end-stage renal disease ... dual specificity protein phosphatase1; RAAS, renin-angiotensin-aldosterone system; Tnpo1, transportin 1. 4.4 Glomerular ...

A new blood pressure medication called lorundrostat has shown promising results in reducing blood pressure among patients ...

Knowing the difference between kidney pain vs. back pain can be difficult because problems with the kidneys may cause dull or sharp pains on the side or along the back. The location of the discomfort, ...

Kidney failure was defined as eGFR <15 ml/min/1.73 m 2 ... and more than 90% of patients received steroids, renin angiotensin aldosterone system inhibitors (RAASis), and other immunosuppressant ...

sNDA accepted for Priority Review Lorundrostat (Mineralys Therapeutics) Highly selective aldosterone synthase inhibitor that reduces aldosterone levels by inhibiting CYP11B2 Treatment of ...

Research analysts at HC Wainwright boosted their Q1 2025 earnings per share (EPS) estimates for Mineralys Therapeutics in a report issued on Wednesday, April 2nd. HC Wainwright analyst M. Caufield now ...

Angion Biomedica ended 2022 in the midst of a strategic review after its lead drug for kidney diseases flamed ... and preclinical-stage ROCK2 and aldosterone synthase inhibitors.

Baxdrostat is a highly selective aldosterone synthase inhibitor; phase 1 studies showed that the therapy caused a sustained, dose-dependent reduction in plasma aldosterone by more than 70% without ...

Mineralys Therapeutics, Inc. (NASDAQ:MLYS – Get Free Report) saw strong trading volume on Wednesday after HC Wainwright ...