Background: The albumin-to-alkaline phosphatase ratio (AAPR) is a predictor of several disease outcomes. However, there is no study about AAPR and acute ischemic stroke outcomes. This study aims to ...

Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 210009, China ...

Considering the intrinsic importance of alkaline phosphatase (ALP) as a biomarker in disease monitoring and as a mostly widely used biolabel for signal transmission in bioanalysis, the development of ...

Juvenile Paget disease (JPD) is a very rare disease, mainly caused by biallelic inactivating mutations in the TNFRSF11B gene that encodes osteoprotegerin. Owing to its rarity, the treatment of JPD is ...

The following is a summary of “Impaired LTB4-induced neutrophil chemotactic directionality in myelodysplastic neoplasms ...

编者按原发性胆汁性胆管炎（Primary Biliary Cholangitis, PBC）是一种免疫介导的慢性肝内胆汁淤积性疾病，主要特征为肝内小胆管损伤，逐渐发展为肝纤维化、肝硬化，具体发病机制尚不清楚。在血清学方面，90%以上的患者抗线粒体抗体 ...

The FDA has fully approved larotrectinib for adult and pediatric patients with solid tumors that harbor an NTRK gene fusion.

Alkaline phosphatase (ALP): ALP, a membrane-bound glycoprotein involved in phosphate metabolism, has several isozymes (intestinal, placental, germ-cell, tissue-nonspecific). Subnormal ALP levels ...

The U.S. Food and Drug Administration (FDA) has granted full approval to Vitrakvi (larotrectinib) for the treatment of adult ...

Full approval of Vitrakvi was based on results from three clinical trials in patients with unresectable or metastatic NTRK ...

A new consensus paper provides an updated evaluation of reference bone turnover markers (BTMs) and newer markers in the diagnosis and management of osteoporosis.