confirming that DASH achieves effective scoring of all SNP types. In each case, the peaks for the pairs of homozygous samples differ by between 5 and 9°C, enabling unambiguous allele scoring.

Synopsis: In a case with implications for the litigious molecular diagnostics space and written description law, Chief Judge Connolly ...

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA ...

In 34,000 of these regions, genetic variations (SNPs) correlate with the methylation patterns, confirming allele-specific methylation and indicating the extent of genetic influence on DNA methylation.

Each SNP position is queried for the presence or absence of a specific base, resulting in a string of binary answers (10, homozygous allele number 1; 01, homozygous allele number 2; 11 ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene ...

Lower pressure ulcer, fall injury and infection rates among I-SNP patients were highlighted in new research published by ATI Advisory Tuesday. The whitepaper aims to inform policymakers about the ...

Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...