PG-012, KGF alternative peptide, is a dimeric peptide composed of cyclic peptides designed to bind specifically to FGFR2b.

England FE, Bordeu I, Ng ME, Bang J, Kim B, Choi J, Cardoso EC, Koo BK, Simons BD#, Lee JH#. Sustained NF-kB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor ...

Aguirre-Ghiso and colleagues determined that when breast cancer DCCs spread to the lung's air sacs (alveoli), they are kept in a dormant state by immune cells known as alveolar macrophages.

Alveolar macrophages (AMs) are specialized resident macrophages tasked with safeguarding the lower respiratory tract. The study reveals that AMs utilize cell division control protein 42 (CDC42 ...

The patients’ cells, however, were unresponsive to CCL-2 and meandered directionless around the chamber. Consistent with lung surfactant build up in the children’s lungs and the monocyte migration ...

Martin Hemberg. More information: Jimmy Tsz Hang Lee et al, Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID ...