(b) in hippocampus. (c-e) Plaque load in nontransgenic and PD-hAPP mice treated with soluble RAGE (+sRAGE). -sRAGE, untreated mice. (f) Image analysis of amyloid load from c-e. (g) Serum from ...

1 Frank P. Smith Laboratories for Neurosurgery, Department of Neurosurgery and Division of Neurovascular Biology, Center for Aging and Developmental Biology, University of Rochester Medical Center ...

Objectives Wild-type transthyretin amyloid cardiomyopathy (wtATTR-CM ... to 12 months in a variety of disease-related variables was explored using Cox regression. Results Change in N-terminal ...

Previous work had investigated amyloid formation in the presence of polymeric nanoparticles 5. The fibrillization kinetics were affected by the peptide examined, the surface chemistry of the ...

We show here that these diverse peptide sequences bind with comparable affinities to the Numb PTB domain at a common binding site on the surface of the protein. The NMR structure of the Numb PTB ...

Biogen’s lack of insider buying and reduced R&D spending raise concerns, but its future growth prospects remain. Find out why ...

Women and those with paternal history of Alzheimer disease have stronger association between Aβ, tau deposition than men or those with maternal history. Valentin Ourry, Ph.D., from McGill ...

There is a large body of evidence that the anthocyanin Queen Garnet facilitates cognitive and memory function and mood in human subjects. Recent research has investigated the plant compounds and their ...

肿瘤是严重威胁人类健康的主要原因之一。研究表明，癌细胞会过表达硫酸乙酰肝素蛋白聚糖（HSPG），并利用结构中的硫酸乙酰肝素（HS）糖链与信号因子结合，促进肿瘤增殖、转移、血管形成。因此，干扰HSPG的生物学功能，诱导细胞凋亡可能为癌症治疗提供新 ...

Neurology experts from UCSF Health presented new clinical research findings and cutting-edge treatment strategies and received distinguished awards recognition at the American Academy of Neurology’s ...

College of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China ...

Learn more Enter a peptide serum. The latest craze in the beauty world by storm, peptides are short chains of amino acids that are commonly used to support the function of your skin barrier and ...