that a buildup of amyloid beta in the brain is the root cause of the disease. Known as the amyloid hypothesis, this theory emerged in the 1980s after researchers identified amyloid plaques as a ...

Although there are many outstanding questions about Alzheimer’s and a significant lack of effective drugs, scientists believe a protein called amyloid-beta plays an important role in the condition.

An illustration depicts cells in an Alzheimer’s-affected brain, with abnormal levels of beta amyloid protein clumping together to form plaques that collect between neurons and disrupt cell function.

Panelists discuss how amyloid-targeting therapies for Alzheimer disease represent a breakthrough drug class that works by binding to and removing beta-amyloid plaques through various mechanisms ...

"These exciting preliminary findings hint very clearly at the potential role of lowering beta amyloid in prevention of Alzheimer's disease," said Maria C. Carrillo, PhD, Alzheimer's Association ...

One year earlier, in June 2021, the US Food and Drug Administration had approved aducanumab, an antibody-targeting beta-amyloid, as a treatment for Alzheimer's, even though the data supporting its use ...

It’s a lab-made antibody that targets beta amyloid, one of two proteins thought to play a critical role in causing Alzheimer’s (the other being tau). In people with Alzheimer’s, a misfolded ...