Discover how combining photodynamic therapy (PDT) with cisplatin enhances lung cancer treatment, promoting tumor cell ...

For the study of OPG and RUNx2 genes, aliquots of RNA (250 ng) were reverse-transcribed with RT 2 First strand kit (SABiosciences, USA) according to manufacturer's instructions. Duplicate plates ...

We then constructed a PPI network and used the MECDE algorithm to identify key genes potentially involved in apoptosis after ICH. Additionally, we identified miRNAs that might regulate apoptotic genes ...

We have shown here that Pml function is crucial for the Fas, TNF, ceramide and IFN apoptotic pathways normally deputed to induce apoptosis upon DNA damage or neoplastic transformation. We have ...

PCL fiber scaffolds loaded with BMSC-derived apoptotic vesicles regulate macrophage ... phenotype by regulating the expression of the CCL-1 gene, promotes fibroblast migration, and initiates ...

According to Dr Ghosh, compounds in F12 demonstrate anticancer potential by inducing apoptosis, killing cancer cells, leaking ...

Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ... Dec. 13, 2024 — Microorganisms produce a wide variety of natural products that can be ...

Mar. 20, 2025 — Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against ...

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality worldwide. Current treatment modalities are few or ...