Researchers explored a unique group of immune cells in the airways of people with severe asthma. The cells, called c-kit+IL-17A+ ILC2s, can be likened to chameleons; they can change their ...
Researchers at McMaster University have made an important discovery in the field of asthma research, identifying a new population of immune cells that may play a crucial role in the severity of asthma ...
enhancers influence the development of Th2 and ILC2. The gene region G900, located close to the GATA3 gene, is currently being investigated for its role in the asthma inflammation pathway.
Here using mouse models, the authors show that maternal asthma is associated with glucocorticoid associated gene changes in foetal offspring ILC2 along with persistent epigenetic changes in these ...
This suggests that controlling intermediate ILC2 levels could keep counts of troublesome white blood cells down, thus potentially preventing severe asthma symptoms, the team said.