SARS-CoV-2, which causes the Coronavirus Disease 2019 (COVID-19) pandemic, has a brain neurotropism through binding to the receptor angiotensin-converting enzyme 2 expressed by neurones and glial ...

Neuroinflammation is triggered by the activation of microglia and astrocytes, which release pro-inflammatory factors that exacerbate neuronal damage. This inflammatory state also disrupts iron ...

This manuscript by Yu et al. demonstrates that activation of caspase-3 is essential for synapse elimination by microglia, but not by astrocytes. This study also reveals that caspase-3 ...

Microglia are special cells in the human brain. Like a diligent ranger overseeing a forest and dealing with infestations and wildfires, microglia scan the brain environment for germs and initiate ...

A bioengineer highlights the potential of low-intensity ultrasound for multiple uses, from enhanced drug delivery to the ...

Preclinical data with the investigational gene therapy INS1202 show improvements in survival and motor performance in ALS.

They spotted many of the genes they suspected of responding to lecanemab expressed in microglia huddled around plaques. There were far more abundant in the lecanemab-treated case than in controls.

As cases of sleep disorders such as insomnia and sleep apnea increase, health experts are raising serious concerns about the ...

A new study suggests that semaglutide, a drug commonly used to treat diabetes, may help protect the brain from the effects of ...