microautophagy and chaperone-mediated autophagy. Liver fibrosis is a consequence of the sustained inflammatory processes underpinning chronic liver disease. Here authors show that autophagy in CD4 ...

为了攻克这一难题，中国医科大学附属第四医院和附属第一医院的研究人员展开了深入的研究。他们将目光聚焦在泛素特异性肽酶 10（Ubiquitin-specific peptidase 10，USP10）上，试图探索其在肺纤维化过程中的作用机制。研究结果令人振奋，他们发现 USP10 可能通过促进 Sirtuin 6（Sirt6）/AKT/mTOR 介导的自噬来减轻肺纤维化，这一发现为 IPF ...

A research team has developed an innovative biomimetic dual-mode magnetic resonance imaging (MRI) nanoprobe for detecting early-stage liver fibrosis in non-alcoholic fatty liver disease (NAFLD).

Boehringer Ingelheim has a second positive trial under its belt for nerandomilast in pulmonary fibrosis, setting up regulatory filings. The new data from the 1,178-patient FIBRONEER-ILD study ...

慢性肝病进展至肝纤维化缺乏有效治疗手段。研究人员开展了 T 细胞自噬在肝纤维化中作用的研究，发现患者 CD4 T 细胞自噬缺陷，且自噬缺陷的 CD4 T 细胞通过 IL-17A 和 GM-CSF 加重肝纤维化，激活自噬可缓解，为肝纤维化治疗提供新方向。

Over the course of five years, I raised one, then two children, managed my cystic fibrosis through exacerbations and a global pandemic, and graduated with honors from veterinary school to achieve my ...

Despite being diagnosed with Cystic Fibrosis in childhood, Julian kept his condition private until an emotional revelation on The Late Late Show with Ryan Tubridy in 2018. He touched the hearts of ...

本届 ISFO 国际类器官大会特设「ISFO 名刊交流」环节，特邀全球顶级期刊《Cell Stem Cell》主编 Sheila Chari 博士，与青年 PI、博士生深度互动。本次活动聚焦类器官及器官芯片领域的前沿及挑战，Chari 博士将分享顶尖期刊论文的评审逻辑、学术叙事的构建技巧及学科交叉的趋势洞察，助力青年学者精准锚定研究方向、提升成果的国际影响力。

The diagnosis is usually reached when the ratio is less than 75% in adults and less than 90% in children. Damage or dysfunction of the airways is associated with conditions such as asthma, COPD, ...