Depression is one of the most common and disabling mental health conditions in the world, affecting over 10% of people ...

Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and chaperone-mediated autophagy. Liver fibrosis is a consequence of the sustained inflammatory processes ...

The occurrence of autophagy was observed by TEM (Tansmission electron microscopy) and immunofluorescence. The expression of proteins involved in AMPK/mTOC1 signaling pathway was detected by western ...

Researchers at Zhejiang University found that acute stress increases natural repair mechanisms in the brain, while chronic ...

Introduction: Lipid accumulation and foam cell formation are significant features that expedite the progression of atherosclerosis (AS). Abnormal autophagy is a key factor in the development of AS.

Department of Ophthalmology, Tongji Hospital Affiliated with Tongji University, Shanghai 200065, People’s Republic of China ...

By binding to an AKAP11 scaffold, PKA engages in poorly understood interactions with autophagy, a key degradation pathway for neuronal cell homeostasis. Mutations in AKAP11 promote schizophrenia and ...

The implication of autophagy in two major pathogenic pathways in SLE suggests the potential to use inhibition of autophagy as a novel treatment target in this frequently severe autoimmune disease.

AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) peptide has garnered attention for its intriguing biological properties ...

Researchers have identified a key enzyme driving forms of Parkinson’s, and have shown how blocking it restores normal ...