Previous studies have indicated the roles of T cell-derived tumor necrosis factor-α (TNFα) and nuclear factor κB (NF-κB) signaling in tumor cell killing, with autophagy inhibiting TNF-α-induced ...

Autophagy is a process by which cellular material is degraded by lysosomes or vacuoles and recycled. Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and ...

There is clear evidence to indicate that senescentcells are remarkably resistant to apoptosis. The intensity of global apoptosis and autophagy clearance significantly declines in humans during aging, ...

My father always insisted on swimming in mountain tarns even in the depths of winter, which we all assumed meant there was ...

We found a degree of mutual exclusivity between autophagy and apoptosis, suggesting activation of programmed cell death if autophagy failed. These results support previous observations that autophagy ...

The accumulation of this protein suggests that autophagy wasn’t working properly. Elevated p62 levels were seen alongside a rise in caspase-3, an enzyme that plays a key role in apoptosis or ...

A recent study reveals that regular cold water swimming can positively alter cellular stress responses. Immersing healthy young men in cold water dail ...

In recent years, autophagy—a fundamental cellular process that mediates the degradation and recycling of cellular components—has emerged as a crucial player in cancer biology, including lung cancer ...

Department of Ophthalmology, Tongji Hospital Affiliated with Tongji University, Shanghai 200065, People’s Republic of China ...