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Now, researchers have bred gray-wolf pups that carry genes of their ancient cousins. By Carl Zimmer Carl Zimmer writes the “Origins” column and has covered de-extinction for more than a decade.

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"Colossal compared the genomes of the dire wolf and the gray wolf, and from about 19,000 genes, they determined that 20 changes in 14 genes gave them a dire wolf," Rawlence said.

A biotech company says it has bred three animals with key physical features of the dire wolf — a species that has been extinct for more than 12,000 years. Colossal Biosciences says it used novel ...

Advertisement Advertisement The dire wolf once roamed an American range that extended as far south as Venezuela and as far north as Canada, but not a single one has been seen in over 10,000 years ...

Nature gave the world the dire wolf 2.6 million years ago, and then, through the hard hand of extinction, took it away—some 10,000 to 13,000 years ago when the last of the species died out.

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(Video production: Laura Bargfeld) This undated photo provided by Colossal Biosciences shows a young wolf that was genetically engineered with similarities to the extinct dire wolf. (Colossal ...