研究者还在中国汉族普通人群中鉴定出131个VUS，在癌症队列中鉴定出41个VUS。在2080名看似健康的个体中，研究者观察到20个反复出现的VUS。最常出现的VUS是BRCA1 c.2726 A > ...

为探究 BRCA 突变、年龄等因素对人输卵管（FT）分子表型的影响，研究人员对 100 多例人 FT 进行多组学分析。结果表明，BRCA1/2 携带者与非携带者在分子表型上差异极小，该研究为卵巢癌高危人群肿瘤发生的预防和早期检测提供新视角。 在女性的生殖系统中，输卵管（Fallopian tube，FT）可是个 “大功臣”，它不仅负责运送卵子，还是受精和早期胚胎发育的 “秘密基地”。然而，近年来， ...

Lenny Santoro was diagnosed with prostate cancer in 2011. Thanks to clinical trials Santoro participated in at the Duke ...

研究人员针对 BRCA 突变携带者开展卵巢癌监测研究，发现 “爆米花” 征可早期诊断，意义重大。 卵巢癌，作为女性生殖系统中极为凶险的 “杀手”，一直威胁着众多女性的生命健康。其中，高等级浆液性卵巢癌（OC）不仅是最具侵袭性的卵巢组织学类型 ...

5-year survival for stage III and IV (%): carriers, 38.1; noncarriers, 24.5 Median survival: p = 0.002 5-year survival for stage III and IV: p < 0.001 [46] Time of first relapse (years): BRCA ...

A comparison of patients with and without BRCA gene mutations receiving prophylactic risk-reduction surgery suggest ...

Me might have filed for bankruptcy, but the transformation it brought to health care over nearly two decades is irreversible, ...

Genetic and genomic testing guide breast cancer risk assessment and treatment, as discussed by Dr. Mark Robson at the Miami ...

Triple negative breast cancer accounts for 15% of cases but causes a disproportionate number of deaths. Learn about symptoms ...

Two sisters recently went viral on TikTok after publicly declaring their decision to get double mastectomies together. The ...

Mutations in BRCA2—a gene known to repair damaged DNA and suppress tumor formation—can predict an individual's predisposition ...

A woman who discovered she had breast cancer after a chance reading of a newspaper article is warning others with Jewish heritage of the increased risk. | ITV News Central ...