他们聚焦于 BRCA1 基因在 M1 巨噬细胞来源的外泌体中的功能，以及其对心肌细胞凋亡和冠状动脉粥样硬化的影响。该研究成果发表在《Cell Biology and Toxicology》杂志上，为冠心病的治疗开辟了新的道路。 研究人员在研究过程中运用了多种关键技术方法。他们从公共 ...

Research by UMass Chan Medical School scientists Sharon Cantor, PhD, and Jenna M. Whalen, PhD, poses a new explanation for how cancer-fighting drugs attack and destroy BRCA1 and BRCA2 tumor cells.

including cancer cells, to repair DNA damage, in men with BRCA1 genetic variants, say the researchers. A linked editorial suggests that the findings pave the way for greater refinement of genetic ...

including cancer cells, to repair DNA damage, in men with BRCA1 genetic variants, say the researchers. A linked editorial suggests that the findings pave the way for greater refinement of genetic ...

Discover the intricate dance between genes, environment, and cancer risk explained by Dr. Ashok Venkitaraman in a ...

Whalen, Ph.D., poses a new explanation for how cancer-fighting drugs attack and destroy BRCA1 and BRCA2 tumor cells. Their work, published in Nature Cancer, illustrates how a small DNA nick—a ...

Cells normally use highly accurate mechanisms to fix these breaks, but some cancers -- particularly those arising from BRCA1 or BRCA2 mutations, such as certain breast and ovarian cancers -- lack ...