Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

The men had either been tested for germline (166), somatic (280), or both types (four) of genetic variants of BRCA1, BRCA2, ATM, CDK12, and PALB2 genes, with a view to starting them on PARP ...

The breast cancer susceptibility gene 1 (BRCA1) protein forms complexes with other protein components to regulate the cellular response to DNA damage. Three studies now report the identification ...

Some of the genes that quickening or extended the age of menopause onset were also linked to cancer risk. This includes the BRCA1 gene mutation made famous by actress Angelina Jolie who underwent ...

Primary care doctors should assess women’s BRCA1 and BRCA2 mutation risks ... It also called for an increase in the number of cancer-specific genetic counselors in the United States.