People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of them doesn't function. For cancer-suppressor genes like BRCA1 ...

The breast cancer susceptibility gene 1 (BRCA1) protein forms complexes with other protein components to regulate the cellular response to DNA damage. Three studies now report the identification ...

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

Even two women with the same cancer gene mutation—such as the 185delAG mutation of BRCA1 found in the Hispanic women featured in "The Secret of San Luis Valley"—may experience very different ...

For example the BRCA1 and BRCA2 genes that can contribute to breast cancer. Mutations in these genes account for approximately 10% of all inherited breast cancer cases detected. Scientists ...

Primary care doctors should assess women’s BRCA1 and BRCA2 mutation risks ... It also called for an increase in the number of cancer-specific genetic counselors in the United States.