Researchers have discovered indigenous Nigerian food plants with anti-cancer properties. The leaves and seeds may halt tumor ...

Specifically, Bax and Casp3 were significantly upregulated ... The effects on apoptosis and inflammation were assessed using RT-PCR, Western blot, and ELISA techniques. For apoptosis, we examined the ...

To assess apoptosis, the tissue sections were subjected to the terminal deoxynucleotidyl ... Bcl-2 while significantly elevating pro-apoptotic Bax levels (Figure 8C), resulting in a pro-apoptotic ...

Unlike typical drug targets involving enzymatic catalysis, BCL-2 functions by protein-protein interaction, which occupies a binding site and prevents apoptosis. Ultimately, this created a hurdle in ...

同时，使用RT-PCR法观察凋亡相关基因Bcl-2及bax的表达情况。所有数据均进行统计学分析，用P<0.05作为显著性标准。 研究成果与发现令人振奋的是，结果表明，人参皂苷Rg3明显诱导了Hela细胞的凋亡。具体而言，在使用Rg3处理后的Hela细胞中，凋亡率随着Rg3浓度的 ...