为改善晚期胃癌治疗现状，研究人员开展靶向 BCL XL 和 MCL 1 的研究，发现联合抑制可增强抗癌活性。 胃癌是全球第五大常见且致命的癌症，多数晚期患者预后差，现有治疗手段效果不佳。为了找到更有效的治疗策略，中国医学科学院 & 北京协和医学院的研究人员 ...

Abstract: The overexpression of B-cell lymphoma-extra large (BCL-xL), an anti-apoptotic protein, plays a pivotal role in various cancers by inhibiting apoptosis and promoting tumor progression. We ...

A recent study published on January 31, 2024, in Nature Aging introduces a potential new drug that could help. Scientists believe this drug can remove harmful “zombie” cells from the liver and slow ...

Cpm - 1285 是一种设计用于靶向并抑制 Bcl - 2 家族蛋白的合成多肽 。它通过化学连接脂肪酸到来源于促凋亡蛋白 Bad 的肽段上而得 。这种结构设计赋予了它一些独特的性质 。从整体结构上看，脂肪酸部分可能有助于其穿透细胞膜，进入细胞内部发挥作用 。其 ...

BCL Industries Ltd., incorporated in the year 1976, is a Small Cap company (having a market cap of Rs 1,196.30 Crore) operating in Agro Processing sector. BCL Industries Ltd. key Products/Revenue ...

BCL Enterprises Ltd., incorporated in the year 1985, is a Small Cap company (having a market cap of Rs 9.21 Crore) operating in Financial Services sector. BCL Enterprises Ltd. key Products/Revenue ...

研究人员针对青少年粒单核细胞白血病（JMML）开展 BCL-2 调控凋亡研究，发现凋亡抵抗机制及潜在疗法。 青少年粒单核细胞白血病研究背景 在儿童血液疾病的领域中，青少年粒单核细胞白血病（Juvenile myelomonocytic leukemia，JMML）是一种极为棘手的存在。它就像隐藏 ...

The Pixel 9 Pro XL is the culmination of everything Google has been working towards, backed by a slate of AI-powered features worth using every day and premium hardware that can rival the best ...