By three-dimensional (3D) reconstruction of serial optical sections, interconnecting hepatic sinusoids and bile canaliculi were detected with Igκ immunostaining between trabecular hepatocytes that ...

Bear bile has been used for thousands of years in traditional Asian medicine. It contains high levels of ursodeoxycholic acid (UDCA) known to be useful for treating liver and gall bladder conditions.

The bile acid sensor TGR5 did not reveal any regional specificity. The protein hydrolysate receptor GPR93 showed highest expression levels in the mid-intestine, peaking in the distal jejunum. The AA ...