Typically, chimeric mice are derived from two components: a mouse embryonic stem (ES) cell clone (that carries a desired mutation) and a blastocyst. At least one of the two components carries a ...

Early embryonic cell polarity and lineage differentiation, which are vital to implantation, and continued embryonic growth climax with the onset of blastocyst formation. These processes are ...

Around day five or six, the embryo reaches a stage called the blastocyst. At this point, it begins to break out of its outer shell, called the zona pellucida. This process is called hatching ...