A hit shows that there is “at least in principle, a molecule out there in the universe that does what I want it to,” he says. “At least it de-risks the concept.” In addition to considering ...

Credit: Anna Moneymaker/ Getty Images US President Donald Trump has issued a broad executive order to lower prescription drug prices in the country, notably including a directive to ease price ...

The three platform deals are long-term bets, but broaden Genentech’s drug discovery capabilities, particularly in small-molecule R&D. The Convelo deal focuses on the development of novel drug ...

A different, more optimized version of the molecule, called PX578, has been advanced to the clinic. That compound recently entered Phase 1 trials.

UCLA scientists have developed a molecule, PP405, that may reverse hair loss by reactivating dormant follicles. Early trials show promising results, and more testing is underway, with FDA approval ...

Here, we explain the discovery of what the researchers have named the "PP405" molecule and how it may potentially be the next big hair loss treatment. The PP405 molecule is "a novel, non-invasive ...

BenevolentAI has entered a two-year agreement with the MRC Technology to investigate new small molecule and antibody drug candidates. The UK-based artificial intelligence company has teamed up ...

Numerous articles and posts that deal with the issue of love intoxication mention phenylethylamine (or PEA), describing it as a specific “love molecule” that is released in the brain and acts ...

Here we report the cryo-EM structure of ligand-free, G protein-free C3aR, providing insights into its inactive conformation. In addition, we determine the structures of C3aR in complex with the ...