为探究帕氏拟杆菌（Parabacteroides distasonis，P. distasonis）对非小细胞肺癌（NSCLC）的调控作用及其对肿瘤免疫的影响，研究人员建立小鼠模型开展相关研究。结果发现 P. distasonis 可促进肿瘤相关巨噬细胞（TAM）分泌 CXCL9，增强 CD8? T 细胞活性，触发针对抗 PD - 1 治疗 ...

Cells were then stained with antibodies (BD Biosciences, Franklin Lakes, NJ unless otherwise stated) against mouse cell surface markers including rat anti-mouse CD45 (clone:30-F11), CD11b (M1/70), ...

研究人员针对外周神经损伤修复中自体移植供体不足、免疫排斥及机械强度不足等问题，通过皮下植入硅胶模具诱导大鼠生成生物源性导管（BCs），结合化学脱细胞和天然交联剂基因肽（GP）处理，构建了具有增强力学性能且保持生物相容性的脱细胞支架。

All cells were stored in serum-free and animal protein free cell cryoculture medium (NCM Biotech) and kept at −80℃. Detect the expression of CD86 and CD206 (reagents produced by BioLegend) molecules ...

The hu CD206 transgenic model is indeed appropriate to delineate the function of the molecule and its possible therapeutic implications in vivo. In this study, the pattern of expression of the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Neoantigen vaccine is a promising breakthrough ...

Indiana University School of Medicine, Indianapolis, IN.

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这些基因之前也被发现在由Melanie Greter团队描述的脑边界相关巨噬细胞（BAMs，即CD45+CD11b+Ly6c-CD206+脑巨噬细胞）中显著表达。进一步的基因表达分析和 ...