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The cell-surface glycoprotein CD44 is involved in a multitude of important physiological functions including cell proliferation, adhesion, migration, hematopoiesis, and lymphocyte activation. The ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Syndecans (SDCs) are ...
By Babul Anunay, Ateet Mishra, Ashish Goel (Freescale Semiconductors Pvt. Ltd) With the increasing complexity of design in today’s fast changing world, the thrust on power saving has increased ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Subcutaneous LCMV infection induces T H 1 cell ...
这种治疗方法上调了CD8和CD4 T细胞中的Tem(CD44 CD62L+-),下调了Tcm(CD44 CD62L)。这些发现表明,Anti-PD1联合wf-UMP不仅能诱导特异性长期保护,还能 ...
与其他组相比,Anti-PD1+wf-UMP治疗可引起持续的抗肿瘤反应,其特点是从Tcm表型向Tem表型的显著过渡。这种治疗方法上调了CD8和CD4 T细胞中的Tem(CD44 CD62L+-),下调了Tcm(CD44 CD62L)。这些发现表明,Anti-PD1联合wf-UMP不仅能诱导特异性长期保护,还能有效预防肿瘤复发。
研究表明,接种 PLGA/Ags 疫苗后,小鼠血清中的抗原特异性 IgG 水平逐渐升高,且在接种后第 42 天,小鼠体内的效应记忆 T 细胞(CD44 + CD62L-)、中枢记忆 T 细胞(CD44 + CD62L + )和记忆 B 细胞(CD19 + CD38-)的比例显著增加。再次接种感染细菌的肿瘤细胞后,接种 PLGA ...
School of Biomolecular and Biomedical Sciences and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland ...
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