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11 天
hLife Letter | CD40信号揭秘:探索未知蛋白质在复合体中的作用
该研究成功构建了能够表达人源CD40分子(hCD40)的基因敲除小鼠模型(hCD40OST)。实验结果表明,hCD40OST小鼠B细胞表型和数量与野生型小鼠一致,并能正常活化;更进一步的研究发现,应用抗hCD40抗体后,hCD40OST小鼠的B细胞表 ...
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