Oral cancer is a cancerous growth in the mouth, on the tongue, lips or gums. The most common type of oral cancer is squamous cell carcinoma.

CU Boulder researchers have uncovered how the enzyme CDK7 drives cell proliferation by controlling a key group of transcription factors, and how inhibiting it can rapidly shut down this process across ...

Breast cancer (BC) is a malignant tumor that has the highest morbidity and mortality rates in the female population, and its high tendency to metastasize is the main cause of poor clinical prognosis.

But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge. New CU Boulder research, published in the journal Science Advances, offers unprecedented insight into how an ...

However, CDK4/6 inhibitors have their limitations. Many tumors develop resistance by switching to alternative CDK pathways, pushing for the next-generation CDK inhibitors to target CDK2, CDK7, and ...

New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation. For organs to develop, grow and regenerate, cells must proliferate.

New CU Boulder research, published in the journal Science Advances, offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives this complex process. The research shows that ...

For decades, cancer researchers and pharmaceutical companies have eyed cyclin-dependent kinase (CDK7) with interest due to its role as a "master regulator" of cell proliferation. CDK7 does this in ...

New CU Boulder research, published in the journal Science Advances, offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives this complex process. The research shows that ...

Lactate, which was traditionally viewed as a metabolic byproduct of anaerobic glycolysis, has emerged as a significant signaling molecule involved in the development of tumors. Current studies ...