Backgrounds: Cutaneous T cell lymphoma (CTCL) is a non-Hodgkin lymphoma characterized by skin infiltration of malignant T cells. The biological overlap between malignant T cells and their normal ...

Mayo Clinic researchers have identified a targeted therapy that could bring relief to people living with lichen planus, a ...

γδ T cells are considered to be potent cells to combat infections and malignancies because of their strategic localization in mucosal tissues, specific recognition of target cells and direct response ...

However, activated NK cells can also kill MSCs. MSCs inhibit T-cell proliferation through the induction of cell-division arrest, which is enhanced by interferon-γ released by activated T cells.

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to ...

CD8 + T cell exhaustion is defined by a unique transcriptional and epigenetic profile that is important to understand for the generation of immunotherapies to treat cancer. Research now shows how ...

Mayo Clinic researchers have identified a targeted therapy that could bring relief to people living with lichen planus, a ...

Jan. 30, 2025 — A new study has highlighted the potential of resveratrol, a natural compound found in grapes, blueberries, and raspberries, to enhance female fertility. The systematic review ...

However, what types of heterogenous cancer cells in primary tumour and how they metastasise to the target organs remain largely undiscovered. Design We performed single-cell RNA sequencing and spatial ...

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