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纳米氧化锌靶向 AMPK/ULK1 通路助力骨再生:开启骨修复新征程
骨缺损发病率上升,现有治疗方法存局限。研究人员开展纳米氧化锌(nZnO)促进骨再生机制研究,发现 nZnO 激活 AMPK-ULK1 通路诱导自噬促进骨再生,且与间充质干细胞(MSCs)联用效果更佳,为骨缺损治疗提供新策略。
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