Furthermore, regulation of STK11 (the gene encoding LKB1) expression at the genetic level can also influence LKB1-AMPK pathway activity (96). These diverse regulatory mechanisms provide rich potential ...

二甲双胍是经典的降糖药物，临床应用已有60多年，且具有降糖之外的多种益处，更多治疗潜力还在不断展现中，素有“神药”之誉。这种源自天然草药山羊豆的药物，为何能拥有如此宽泛的功效？尽管目前为止二甲双胍的作用机制尚未完全阐明，但众多证据 ...

本文通过对藏族和汉族全基因组测序，发现多个受选择区域，揭示 MCUR1 基因在高原适应（HAA）中调节红细胞生成的新机制。 研究背景 青藏高原平均海拔超 4000 米，氧气稀薄、气候寒冷，对人类生存构成巨大挑战。然而，藏族人却在这片土地上成功定居数千年 ...

Rapid activation of adenosine monophosphate-activated protein kinase (AMPK) induces phosphorylation of mitochondrial-associated proteins, a process by which phosphate groups are added to regulate ...

Isolation and Identification of Compounds from Bioactive Extracts of Taraxacum officinale Weber ex F. H. Wigg. (Dandelion) as a Potential Source of Antibacterial Agents.

Key Laboratory for Chemical Biology of Fujian Province, MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen ...

In a blow for many of the tens of thousands of Queenslanders still without power almost a week after then-Cyclone Alfred started knocking down trees and power lines, the damage has been described ...