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骨缺损发病率上升,现有治疗方法存局限。研究人员开展纳米氧化锌(nZnO)促进骨再生机制研究,发现 nZnO 激活 AMPK-ULK1 通路诱导自噬促进骨再生,且与间充质干细胞(MSCs)联用效果更佳,为骨缺损治疗提供新策略。
Found in plants like barberry and Oregon grape, this bitter-tasting compound activates an enzyme called AMPK that helps cells take in glucose. Some studies show it can lower blood sugar nearly as ...
Mechanistic studies revealed that the mito-condition medium activates the AMPK pathway, a crucial cellular energy sensor, driving upregulation of mitochondrial biogenesis genes such as TFAM.
这几天「吉卜力」火爆出圈(实测 GPT-4o 吉卜力漫画风),甚至引出了一些官司。这可能也是导致 ChatGPT 开始频繁拒绝生成吉卜力风格的部分原因。