TAM 受体家族在肿瘤免疫领域愈发受到关注 ... 在胶质母细胞瘤中，阻断 MERTK 能够减少 CD206 + M2 样巨噬细胞的数量，联合放疗可显著减缓肿瘤生长，并增强 M1 样巨噬细胞的激活，从而改善炎症免疫反应。 TYRO3 受体的高表达与多种癌症相关，包括鳞状细胞癌 ...

Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States Alnylam ...

Background: Tumor-associated neutrophils (TANs) play crucial roles in tumor progression, immune response modulation, and the therapeutic outcomes. Despite significant advancements in TAN research, a ...