Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity.

Notch 信号通路对胚胎发育和 CSC 的增殖、维持及分化至关重要 ... 通过功能化修饰使其携带能特异性结合 CSC 表面标记（如 CD44、CD133 和 EpCAM）的配体，实现对 CSCs 的精准靶向。例如，金纳米颗粒与抗 CD44 抗体结合，可在体外和体内选择性杀伤 CSCs。

CD44 is the earliest identified and currently the most established and typical surface ... However, studies targeting exosomes in GCSCs are relatively scarce and may be a breakthrough for future ...

Ischemic heart disease (IHD) is a leading cause of disability and death worldwide, with immune regulation playing a crucial role in its pathogenesis. Various immune cells are involved, and as one of ...

aMedical Clinic 1, Department of Gastroenterology, Ludwig Demling Endoscopy Center of Excellence, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany ...

Objectives In this study, we employ a multiomic approach to identify major cell types and subsets, and their transcriptomic profiles within the infrapatellar fat pad (IFP), and to determine ...

Drew Barrymore Reveals Being 'Jealous' of Other Kids Growing Up; Says It's 'Devastating' Not Having 'Traditional Family Dynamic' How Kate Middleton Deals With 'Fourth Child' Prince William? Royal ...

We thank Professor John L. Rubenstein for his comments, suggestions, and edits. We are grateful to Professor Hua Han for sharing the Rbpj floxed mice, and Professor Jean M. Hebert for sharing ...