The nicotinic acetylcholine receptors (nAChRs) are the most well understood membrane receptors for neurotransmitters at the structural and functional level. They are integral allosteric membrane ...

Advancements in chimeric antigen receptor engineered T-cell (CAR-T) therapy have revolutionized treatment for several cancer types over the past decade. Despite this success, obstacles including the ...

Based on this study, it was found that berberine treatment could reduce podocyte injury by downregulating TGF-β1 receptor expression, which reduced apoptosis and increased podocyte adhesion ability ...

Drug discovery efforts have expanded beyond the traditional approaches of small molecules and antibodies to include cells.