By targeting this enzyme, we can develop more effective treatments for glioblastoma, a brain tumor with very few effective treatment options," said study lead author Deliang Guo, Ph.D., the ...

Newco Brink Therapeutics SAS is poised to work on the next chapter in genome editing after raising €3.5 million (US$4 million) in seed funding to discover and develop programmable recombinase enzymes.

Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China Key Laboratory of Pharmaceutical Engineering of ...

Pfizer turned its focus to developing a once-daily version of danuglipron. High levels of liver enzymes are a potential sign of liver toxicity. Pfizer said that across more than 1,400 danuglipron ...

SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease. Molecular Neurodegeneration , 2025; 20 (1) DOI: 10.1186/s13024-024-00788-8 Cite This Page : ...

A research team at the Institute for Basic Science (IBS) has identified a previously unknown enzyme, SIRT2, that plays a key role in memory loss associated with Alzheimer's disease (AD).

Get Instant Summarized Text (Gist) A new family of enzymes, Ssn endonucleases, has been identified that can specifically target and cut single-stranded DNA. This discovery overcomes a previous ...

Chair of Industrial Organic Chemistry and Biotechnology, Faculty of Chemistry, Bielefeld University, Universitätsstr. 25, 33615 Bielefeld, Germany ...

The research, led by Steven Frese, an assistant professor in the Department of Nutrition at the University’s College of Agriculture, Biotechnology & Natural Resources, has identified three previously ...

Mutations or deletions in the gene for POLG yield defective polymerases that cannot stay on the mtDNA template, thus leaving the enzyme’s tasks incomplete. PZL-A binds to an allosteric site on ...