Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA The Anaphase Promoting Complex/Cyclosome (APC/C) plays an indispensable role in regulating timely cell cycle transition from ...

Thus, Meru couples spindle orientation with cell polarity and provides a cell cycle-dependent cue for spindle tethering. How spindle-tethering complexes read the cell polarity axis during asymmetric ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

HR and non-homologous end joining (NHEJ) repair pathway compete to repair DNA double-strand breaks (DSBs) throughout the cell cycle and play crucial roles in determining cell fate. Mitotic progression ...

“The amount of inflammation is significantly elevated in the follicular phase, or first half, of the menstrual cycle in female patients with sickle cell disease,” said lead researcher D ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The correction of erroneous ...

Period-driven inflammation could influence the risk of pain events among women with sickle cell disease Levels of C-reactive protein increase among women with sickle cell disease during the first ...

The landmark discovery of the BCL-2 gene and its function marked the inhibition of apoptotic cell death as a crucial mechanism driving cancer development. This new review brings together some of ...